Increase Energy and Endurance
Citrulline can modulate enzymes involved in glycogen breakdown, glycogenolysis, and enzymes that convert glucose to ATP through glycolysis. This action shifts muscle from aerobic to anaerobic metabolism, reducing the rate at which the body uses up ATP and phosphocreatine, while also accelerating their replenishment. This means more energy is available to the muscles for longer working sets, a reduction in muscle fatigue and longer cardio sessions!
Reduces Ammonia and Prevents Muscle Burnout
Ammonia acts as a signal for muscle fatigue when it accumulates by inhibiting conversion of pyruvate to acetyl-CoA, blocking muscle contraction. Citrulline buffers ammonia, via the urea cycle, increasing ornithine levels, and promoting ureogenesis (production of urea) and bicarbonate reabsorption, which preserves bicarbonate and allows it to perform its buffering action against ammonia.
Helps Increase NO Production
Citrulline increases plasma levels of L-arginine in a dose-dependent manner. It has been shown that supplementing with citrulline malate can help increase the levels of L-arginine, which in turn allows for more availability of L-arginine for the NOS pathway of NO production. More NO means greater blood flow and better nutrient delivery to working muscles.
Helps Restore Protein Synthesis
Citrulline may help restore muscle protein synthesis rates and muscular function simply by improving nitrogen balance and encouraging use of amino acids-particularly BCAA in muscles during exercise. Improved nitrogen retention and presence of BCAA helps signal the mTOR pathway of protein synthesis.
NOS Production Support - Vitamin C
This antioxidant helps increase the activity of the enzyme nitric oxide synthase, the protein that produces nitric oxide. It also helps sustain NO bioavailability.
Enhances Absorption - AstraGin™
CITRULLINE MALATE 2000™ is formulated with the patented absorption complex AstraGin™, which has been clinically shown to significantly improve nutrient absorption, ensuring maximum absorption with every serving of CITRULLINE MALATE 2000™.
SD Pharmaceuticals Citrulline Malate 2000 Recommend Use or Purpose
Helps the body metabolize fats and proteins. Helps in the development and maintenance of bones, cartilage, teeth and gums. Helps in connective tissue formation and in wound healing. An antioxidant for the maintenance of good health.
Recommended Dose (Adults > 18 years):
1 scoop(s) 1 to 2 time(s) per day. Mix product in 150 - 200 mL of liquid (water, juice, etc.) immediately before consumption.
Duration of Use:
Consult a health care practitioner for use beyond 3 months.